B cell depletion benefits ME/CFS patients

Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) showed clinical improvement after extended treatment with the anti-B-cell monoclonal antibody rituximab. This result suggests that in a subset of patients, ME/CFS might be an autoimmune disease. Rituximab is a monoclonal antibody against a protein on the surface of B cells known as …

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The Emerging Role of Autoimmunity in ME/CFS

From Molecular Neurobiology, 2013 Sep 26, by G Morris, M Berk, P Galecki & M Maes. Research Summary from the authors: “The World Health Organization classifies myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) as a nervous system disease. Together with other diseases under the G93 heading, ME/cfs shares a triad of abnormalities involving …

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