B cell depletion benefits ME/CFS patients

Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) showed clinical improvement after extended treatment with the anti-B-cell monoclonal antibody rituximab. This result suggests that in a subset of patients, ME/CFS might be an autoimmune disease. Rituximab is a monoclonal antibody against a protein on the surface of B cells known as…

Continue reading

The role of viruses, bacteria and fungal biotoxin exposure in CFS

Should people with ME/CFS be lumped into a “fatigue of unknown origin” basket and just given counselling and an exercise program? This new paper from Dr Michael Maes and colleagues says no! They suggest that Parvoviruses, HHV6, variants of Epstein-Barr Virus, Cytomegalovirus, Mycoplasma, Borrelia burgdorferi, chronic fungal infections or other…

Continue reading